Percutaneous Cryoablation for Renal Cell Carcinoma
Main Article Content
Keywords
Cryoablation, Cryoprobe, Radio frequency ablation, renal cell carcinoma
Abstract
Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults. Nephron sparing resection (partial nephrectomy) has been the “gold standard” for the treatment of resectable disease. With the widespread use of cross sectional imaging techniques, more cases of renal cell cancers are detected at an early stage, i.e. stage 1A or 1B. This has provided an impetus for expanding the nephron sparing options and especially, percutaneous ablative techniques. Percutaneous ablation for RCC is now performed as a standard therapeutic nephron-sparing option in patients who are poor candidates for resection or when there is a need to preserve renal function due to comorbid conditions, multiple renal cell carcinomas, and/or heritable renal cancer syndromes. During the last few years, percutaneous cryoablation has been gaining acceptance as a curative treatment option for small renal cancers. Clinical studies to date indicate that cryoablation is a safe and effective therapeutic method with acceptable short and long term outcomes and with a low risk, in the appropriate setting. In addition it seems to offer some advantages over radio frequency ablation (RFA) and other thermal ablation techniques for renal masses.
References
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12. Rosenberg MD, Kim CY, Tsivian M, Suberlak MN, Sopko DR, Polascik TJ, Nelson RC. Percutaneous cryoablation of renal lesions with radiographic ice ball involvement of the renal sinus: analysis of hemorrhagic and collecting system complications. AJR Am J Roentgenol. 2011;196(4):935-9. Doi: http://dx.doi.org/10.2214/AJR.10.5182
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14. Long CJ, Kutikov A, Canter DJ, Egleston BL, Chen DY, Viterbo R, Boorjian SA, Uzzo RG. Percutaneous vs surgical cryoablation of the small renal mass: is efficacy compromised? BJU Int. 2011;107(9):1376-80.
Doi: http://dx.doi.org/10.1111/j.1464-410X.2010.09851.x
15. Atwell TD, Callstrom MR, Farrell MA, Schmit GD, Woodrum DA, Leibovich BC, Chow GK, Patterson DE, Blute ML, Charboneau JW. Percutaneous renal cryoablation: local control at mean 26 months of follow up. J Urol. 2010,184(4):1291-5. Doi: http://dx.doi.org/10.1016/j.juro.2010.06.003
16. Silverman SG, Tuncali K, van Sonnenberg E, Morrison PR, Shankar S, Ramaiya N, Richie JP. Renal tumors: MR imaging-guided percutaneous cryotherapy—initial experience in 23 patients. Radiology. 2005;236(2):716-24. Doi: http://dx.doi.org/10.1148/radiol.2362041107
17. Rodriguez R, Cizman Z, Hong K, Koliatsos A, Georgiades C. Prospective analysis of the safety and efficacy of percutaneous cryoablation for pT-1NxMx biopsy-proven renal cell carcinoma. Cardiovasc Intervent Radiol. 2011;34(3):573-8. Doi: http://dx.doi.org/10.1007/s00270-010-9934-7
18. Littrup PJ et al. CT-guided percutaneous cryotherapy of renal masses. J Vasc Interv Radiol. 2007;18(3):383-92. Doi: http://dx.doi.org/10.1016/j.jvir.2006.12.007
19. Atwell TD, Farrell MA, Leibovich BC, Callstrom MR, Chow GK, Blute ML, Charboneau JW. Percutaneous renal cryoablation: experience treating 115 tumors. J Urol. 2008;179(6):2136-40; discussion 2140-1.
Doi: http://dx.doi.org/10.1016/j.juro.2008.01.144.
20. Buy X1, Lang H, Garnon J, Sauleau E, Roy C, Gangi A. Percutaneous Renal Cryoablation: Prospective Experience Treating 120 Consecutive Tumors. AJR Am J Roentgenol. 2013;201(6):1353-61.
Doi: http://dx.doi.org/10.2214/AJR.13.11084
21. Georgiades CS, Rodriguez R. Efficacy and safety of percutaneous cryoablation for stage 1A/B renal cell carcinoma: results of a prospective, single-arm, 5-year study. Cardiovasc Intervent Radiol. 2014;37(6):1494-9. Doi: http://dx.doi.org/10.1007/s00270-013-0831-8
22. Campbell SC, Krishnamurthi V, Chow G, Hale J, Myles J, Novick AC. Renal cryosurgery: experimental evaluation of treatment parameters. Urology. 1998;52(1):29-33; discussion 33-4.
Doi: http://dx.doi.org/10.1016/S0090-4295(98)00169-1
23. Georgiades CS, Rodriguez R, Azene E, Weiss C, Chaux A, Gonzalez-Roibon N, Netto G. Determination of the Nonlethal Margin Inside the Visible "Ice-Ball" During Percutaneous Cryoablation of Renal Tissue. Cardiovasc Intervent Radiol. 2013;36(3):783-90. Doi: http://dx.doi.org/10.1007/s00270-012-0470-5
24. Clarke DM, Robilotto AT, Rhee E, VanBuskirk RG, Baust JG, Gage AA, Baust JM. Cryoablation of renal cancer: variables involved in freezing-induced cell death. Technol Cancer Res Treat. 2007;6(2):69-79.
25. Allen BC, Remer EM. Percutaneous Cryoablation of Renal Tumors: Patient Selection, Technique, and Postprocedural Imaging. Radiographics. 2010;30(4):887-900. Doi: http://dx.doi.org/10.1148/rg.304095134.
26. Beemster P, Phoa S, Wijkstra H, de la Rosette J, Laguna P. Follow-up of renal masses after cryosurgery using computed tomography: enhancement patterns and cryolesion size. BJU Int. 2008;101(10):1237-42. Doi: http://dx.doi.org/10.1111/j.1464-410X.2007.07437.x
27. Kapoor A, Wang Y, Dishan B, Pautler SE. Update on cryoablation for treatment of small renal mass: oncologic control, renal function preservation, and rate of complications. Curr Urol Rep. 2014;15(4):396.
Doi: http://dx.doi.org/10.1007/s11934-014-0396-3
2. Fergany AF, Hafez KS, Novick AC. Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year follow-up. J Urol. 2000;163(2):442-5.
Doi: http://dx.doi.org/10.1016/S0022-5347(05)67896-2
3. Woldu SL et al. Comparison of Renal Parenchymal Volume Preservation Between Partial Nephrectomy, Cryoablation, and Radiofrequency Ablation. J Endourol. March 2015, epub ahead of print.
Doi: http://dx.doi.org/10.1089/end.2014.0866
4. Campbell SC et al. Guidelines for management of the clinical T1 renal mass. J Urol. 2009;182(4):1271-9. Doi: http://dx.doi.org/10.1016/j.juro.2009.07.004
5. Kunkle DA, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass: a meta-analysis. Cancer. 2008;113(10):2671-80. Doi: http://dx.doi.org/10.1002/cncr.23896
6. Venkatesan AM, Wood BJ, Gervais DA. Percutaneous Ablation in the Kidney. Radiology. 2011;261(2):375-91. Doi: http://dx.org/10.1148/radiol.11091207.
7. Breen DJ, Rutherford EE, Stedman B, Roy-Choudhury SH, Cast JE, Hayes MC, Smart CJ. Management of renal tumors by image-guided radiofrequency ablation: experience in 105 tumors. Cardiovasc Intervent Radiol. 2007;30(5):936-42. Doi: http://dx.doi.org/10.1007/s00270-007-9090-x
8. Zagoria RJ, Traver MA, Werle DM, Perini M, Hayasaka S, Clark PE. Oncologic efficacy of CT-guided percutaneous radiofrequency ablation of renal cell carcinomas. AJR Am J Roentgenol. 2007 Aug;189(2):429-36. Doi: http://dx.doi.org/10.2214/AJR.07.2258
9. Psutka SP, Feldman AS, McDougal WS, McGovern FJ, Mueller P, Gervais DA. Long-Term Oncologic Outcomes After Radiofrequency Ablation for T1 Renal Cell Carcinoma. Eur Urol. 2013;63(3):486-92.
Doi: http://dx.doi.org/10.1016/j.eururo.2012.08.062
10. Olweny EO, Park SK, Tan YK, Best SL, Trimmer C, Cadeddu JA. Radiofrequency ablation versus partial nephrectomy in patients with solitary clinical T1a renal cell carcinoma: comparable oncologic outcomes at a minimum of 5 years of follow-up. Eur Urol. 2012;61(6):1156-61. Doi: http://dx.doi.org/10.1016/j.eururo.2012.01.001
11. Janzen NK, Perry KT, Han KR, Kristo B, Raman S, Said JW, Belldegrun AS, Schulam PG. The effects of intentional cryoablation and radio frequency ablation of renal tissue involving the collecting system in a porcine model. J Urol. 2005;173(4):1368-74. Doi: http://dx.doi.org/10.1097/01.ju.0000147014.69777.06
12. Rosenberg MD, Kim CY, Tsivian M, Suberlak MN, Sopko DR, Polascik TJ, Nelson RC. Percutaneous cryoablation of renal lesions with radiographic ice ball involvement of the renal sinus: analysis of hemorrhagic and collecting system complications. AJR Am J Roentgenol. 2011;196(4):935-9. Doi: http://dx.doi.org/10.2214/AJR.10.5182
13. Atwell TD et al. Percutaneous ablation of renal masses measuring 3.0 cm and smaller: comparative local control and complications after radiofrequency ablation and cryoablation. AJR Am J Roentgenol. 2013;200(2):461-6. Doi: http://dx.doi.org/10.2214/AJR.12.8618
14. Long CJ, Kutikov A, Canter DJ, Egleston BL, Chen DY, Viterbo R, Boorjian SA, Uzzo RG. Percutaneous vs surgical cryoablation of the small renal mass: is efficacy compromised? BJU Int. 2011;107(9):1376-80.
Doi: http://dx.doi.org/10.1111/j.1464-410X.2010.09851.x
15. Atwell TD, Callstrom MR, Farrell MA, Schmit GD, Woodrum DA, Leibovich BC, Chow GK, Patterson DE, Blute ML, Charboneau JW. Percutaneous renal cryoablation: local control at mean 26 months of follow up. J Urol. 2010,184(4):1291-5. Doi: http://dx.doi.org/10.1016/j.juro.2010.06.003
16. Silverman SG, Tuncali K, van Sonnenberg E, Morrison PR, Shankar S, Ramaiya N, Richie JP. Renal tumors: MR imaging-guided percutaneous cryotherapy—initial experience in 23 patients. Radiology. 2005;236(2):716-24. Doi: http://dx.doi.org/10.1148/radiol.2362041107
17. Rodriguez R, Cizman Z, Hong K, Koliatsos A, Georgiades C. Prospective analysis of the safety and efficacy of percutaneous cryoablation for pT-1NxMx biopsy-proven renal cell carcinoma. Cardiovasc Intervent Radiol. 2011;34(3):573-8. Doi: http://dx.doi.org/10.1007/s00270-010-9934-7
18. Littrup PJ et al. CT-guided percutaneous cryotherapy of renal masses. J Vasc Interv Radiol. 2007;18(3):383-92. Doi: http://dx.doi.org/10.1016/j.jvir.2006.12.007
19. Atwell TD, Farrell MA, Leibovich BC, Callstrom MR, Chow GK, Blute ML, Charboneau JW. Percutaneous renal cryoablation: experience treating 115 tumors. J Urol. 2008;179(6):2136-40; discussion 2140-1.
Doi: http://dx.doi.org/10.1016/j.juro.2008.01.144.
20. Buy X1, Lang H, Garnon J, Sauleau E, Roy C, Gangi A. Percutaneous Renal Cryoablation: Prospective Experience Treating 120 Consecutive Tumors. AJR Am J Roentgenol. 2013;201(6):1353-61.
Doi: http://dx.doi.org/10.2214/AJR.13.11084
21. Georgiades CS, Rodriguez R. Efficacy and safety of percutaneous cryoablation for stage 1A/B renal cell carcinoma: results of a prospective, single-arm, 5-year study. Cardiovasc Intervent Radiol. 2014;37(6):1494-9. Doi: http://dx.doi.org/10.1007/s00270-013-0831-8
22. Campbell SC, Krishnamurthi V, Chow G, Hale J, Myles J, Novick AC. Renal cryosurgery: experimental evaluation of treatment parameters. Urology. 1998;52(1):29-33; discussion 33-4.
Doi: http://dx.doi.org/10.1016/S0090-4295(98)00169-1
23. Georgiades CS, Rodriguez R, Azene E, Weiss C, Chaux A, Gonzalez-Roibon N, Netto G. Determination of the Nonlethal Margin Inside the Visible "Ice-Ball" During Percutaneous Cryoablation of Renal Tissue. Cardiovasc Intervent Radiol. 2013;36(3):783-90. Doi: http://dx.doi.org/10.1007/s00270-012-0470-5
24. Clarke DM, Robilotto AT, Rhee E, VanBuskirk RG, Baust JG, Gage AA, Baust JM. Cryoablation of renal cancer: variables involved in freezing-induced cell death. Technol Cancer Res Treat. 2007;6(2):69-79.
25. Allen BC, Remer EM. Percutaneous Cryoablation of Renal Tumors: Patient Selection, Technique, and Postprocedural Imaging. Radiographics. 2010;30(4):887-900. Doi: http://dx.doi.org/10.1148/rg.304095134.
26. Beemster P, Phoa S, Wijkstra H, de la Rosette J, Laguna P. Follow-up of renal masses after cryosurgery using computed tomography: enhancement patterns and cryolesion size. BJU Int. 2008;101(10):1237-42. Doi: http://dx.doi.org/10.1111/j.1464-410X.2007.07437.x
27. Kapoor A, Wang Y, Dishan B, Pautler SE. Update on cryoablation for treatment of small renal mass: oncologic control, renal function preservation, and rate of complications. Curr Urol Rep. 2014;15(4):396.
Doi: http://dx.doi.org/10.1007/s11934-014-0396-3
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Published
Jun 9, 2015
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Percutaneous Cryoablation for Renal Cell Carcinoma. (2015). Journal of Kidney Cancer and VHL, 2(3), 105-113. https://doi.org/10.15586/jkcvhl.2015.34
Section
Kidney Cancer: Review Articles
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